INT-06

Endogenous Interferents: Beyond Hemolysis, Lipemia, and Icterus

Certainly the “big 3” are important, but other endogenous metabolites may also interfere with common laboratory tests. Among the endogenous interferents, these seven circulate at relatively high concentration and can interfere with spectrophotometric assays: creatinine, glucose, glycerol, lactate, pyruvate, uric acid, and urea. CLSI has recommended concentrations and protocols for testing these potential interferents (Interference Testing in Clinical Chemistry; Approved Guidelines (EP07-A2), and Sun Diagnostics now has a kit to simplify testing for these endogenous metabolites: INT-06. The metabolites come in individual vials at 20-fold the CLSI recommended test concentrations so that they are easily spiked into serum or urine pools for analysis.

ASSURANCE Endogenouse Interferents Test Kit
PN: INT-06 Price: $600
Includes: One vial of each component, 1ml
Individual Interferents $100/vial
Interferent ASSURANCE
Concentration*
Component PN
CREATININE 300 mg/dL INT-06C
GLUCOSE 20,000 mg/dL INT-06GLU
GLYCEROL 340 mg/dL INT-06GLY
LACTATE 1,800 mg/dL INT-06LAC
PYRUVATE 100 mg/dL INT-06PYR
BLOOD UREA NITROGEN 2,400 mg/dL INT-06BUN
URIC ACID 470 mg/dL

INT-06UA

(Includes NaOH for control)

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